Article
Dopaminergic gene polymorphisms and cognitive function in a north Indian schizophrenia cohort.
Journal of psychiatric research - 1 Nov 2013
Kukshal Prachi, Kodavali Venkat Chowdari, Srivastava Vibhuti, Wood Joel, McClain Lora, Bhatia Triptish, Bhagwat A M, Deshpande Smita Neelkanth, Nimgaonkar Vishwajit Laxmikant, Thelma B K
Abstract excerpt
BACKGROUND: Associations of polymorphisms from dopaminergic neurotransmitter pathway genes have mostly been reported in Caucasian ancestry schizophrenia (SZ) samples. As studies investigating single SNPs with SZ have been inconsistent, more detailed analyses utilizing multiple SNPs with the diagnostic phenotype as well as cognitive function may be more informative. Therefore, these analyses were conducted in a...
Topics
- Case-Control Studies
- Catechol O-Methyltransferase
- Cognition Disorders
- Cohort Studies
- Dopamine Plasma Membrane Transport Proteins
- Family Health
- Female
- Genetic Association Studies
- Genetic Predisposition to Disease
- Genotype
- Humans
- India