Article
[Developing FGFR inhibitors as potential anti-cancer agents].
Acta pharmaceutica Hungarica - 1 Jan 2013
Zsákai Lilian, Németh Gábor, Szántai-Kis Csaba, Greff Zoltán, Horváth Zoltán, Szokol Bálint, Baska Ferenc, Boon Tin Chuad, Orfi Lászlo, Kéri Györgya
Abstract excerpt
Fibroblast Growth Factor Receptor (FGFR) family is a sequentially highly related subgroup of membrane proteins consisting of four tyrosine kinase type enzyme: FGFR1, FGFR2, FGFR3 and FGFR4. These are kinases of great interest in a wide spectrum of physiological processes such as tissue repair via controlling cell proliferation. As initiatiors of cell proliferation, in some cases they have leading roles in several...
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