Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MiR-223 modulates multidrug resistance via downregulation of ABCB1 in hepatocellular carcinoma cells

7 Aug 2013

Abstract excerpt

Multidrug resistance (MDR) has become a major impediment to a successful treatment for liver cancer patients, and one of the common reasons for MDR is the activation of ABCB1 gene, leading to the over-expression of P-glycoprotein (P-gp), which conferred cancer cells be resistant to a broad range of anticancer drugs. MicroRNAs (miRNAs) are a class of short, non-coding RNA moleculars that can regulate gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Circular RNAs in diseases
Share to Drug Transport and Resistance Mechanisms
Share to MicroRNA in disease regulation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23925649
DOI: 10.1177/1535370213497321

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MiR-223 modulates multidrug resistance via downregulation of ABCB1 in hepatocellular carcinoma cellsPMID 23925649Read ↗

MicroRNA-873 mediates multidrug resistance in ovarian cancer cells by targeting ABCB1Semantic proximity Read ↗

Drug Resistance in Hepatocellular Carcinoma: Theoretical Basis and Therapeutic AspectsSemantic proximity Read ↗

Efflux ABC transporters in drug disposition and their posttranscriptional gene regulation by microRNAsSemantic proximity Read ↗

miRNAs modulate the drug response of tumor cells.Semantic proximity Read ↗

Involvement of miR-133a and miR-326 in ADM resistance of HepG2 through modulating expression of ABCC1Semantic proximity Read ↗

Molecular Pathways: Regulation and Therapeutic Implications of Multidrug ResistanceSemantic proximity Read ↗

Regulation of multidrug resistance by microRNAs in anti-cancer therapySemantic proximity Read ↗

Adenosine triphosphate-binding cassette transporter genes up-regulation in untreated hepatocellular carcinoma is mediated by cellular microRNAs.Semantic proximity Read ↗

Possible Role of microRNA-122 in Modulating Multidrug Resistance of Hepatocellular CarcinomaSemantic proximity Read ↗

MDR1/P-Glycoprotein (ABCB1) as Target for RNA Interference-Mediated Reversal of Multidrug ResistanceSemantic proximity Read ↗

miR-497 modulates multidrug resistance of human cancer cell lines by targeting BCL2Semantic proximity Read ↗

MiR-199a-3p enhances cisplatin sensitivity of cholangiocarcinoma cells by inhibiting mTOR signaling pathway and expression of MDR1Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.