Article
Aromatic residue on β→α loop 1 in the catalytic domain is important to the transglycosylation specificity of glycoside hydrolase family 31 α-glucosidase.
Bioscience, biotechnology, and biochemistry - 1 Jan 2013
Song Kyung-Mo, Okuyama Masayuki, Nishimura Mariko, Tagami Takayoshi, Mori Haruhide, Kimura Atsuo
Abstract excerpt
The specificity for the α-1,4- and α-1,6-glucosidic linkages varies among glycoside hydrolase family 31 α-glucosidases. This difference in substrate specificity has been considered to be due to the difference in an aromatic residue on β→α loop 1 in the catalytic domain with a (β/α)8 barrel fold;...
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