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Article

Bacterial cyclic AMP-phosphodiesterase activity coordinates biofilm formation.

PloS one - 1 Jan 2013

Kalivoda Eric J, Brothers Kimberly M, Stella Nicholas A, Schmitt Matthew J, Shanks Robert M Q

Abstract excerpt

Biofilm-related infections are a major contributor to human disease, and the capacity for surface attachment and biofilm formation are key attributes for the pathogenesis of microbes. Serratia marcescens type I fimbriae-dependent biofilms are coordinated by the adenylate cyclase, CyaA, and the cyclic 3',5'-adenosine monophosphate (cAMP)-cAMP receptor protein (CRP) complex. This study uses S. marcescens as a model...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23923059
DOI: 10.1371/journal.pone.0071267
PMCID: PMC3726613

Genes

CRP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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