Small intragenic deletion in FOXP2 associated with childhood apraxia of speech and dysarthria.

Abstract excerpt

Relatively little is known about the neurobiological basis of speech disorders although genetic determinants are increasingly recognized. The first gene for primary speech disorder was FOXP2, identified in a large, informative family with verbal and oral dyspraxia. Subsequently, many de novo and familial cases with a severe speech disorder associated with FOXP2 mutations have been reported. These mutations...

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• Apraxias
• Child
• Forkhead Transcription Factors
• Motor Skills
• Pedigree