Article
Candidate gene association study implicates p63 in the etiology of nonsyndromic bladder-exstrophy-epispadias complex.
Birth defects research. Part A, Clinical and molecular teratology - 1 Dec 2013
Qi Lihong, Wang Mei, Yagnik Garima, Mattheisen Manuel, Gearhart John P, Lakshmanan Yegappan, Ebert Anne-Karolin, Rösch Wolfgang, Ludwig Michael, Draaken Markus, Reutter Heiko, Boyadjiev Simeon A
Abstract excerpt
BACKGROUND: Bladder-exstrophy-epispadias complex (BEEC) is a severe congenital anomaly that represents a spectrum of urological abnormalities where parts or all of the distal urinary tract fail to close during development. Multiple lines of evidence strongly suggested p63 as a plausible candidate gene. We conducted a candidate gene association study to further investigate the role of p63 in human BEEC. METHODS:...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.