Article
Identification of regions associated with variation in sensitivity to food-related odors in the human genome.
Current biology : CB - 19 Aug 2013
McRae Jeremy F, Jaeger Sara R, Bava Christina M, Beresford Michelle K, Hunter Denise, Jia Yilin, Chheang Sok Leang, Jin David, Peng Mei, Gamble Joanna C, Atkinson Kelly R, Axten Lauren G, Paisley Amy G, Williams Liam, Tooman Leah, Pineau Benedicte, Rouse Simon A, Newcomb Richard D
Abstract excerpt
Humans vary in their ability to smell numerous odors [1-3], including those associated with food [4-6]. Odor sensitivity is heritable [7-11], with examples linking genetic variation for sensitivity to specific odors typically located near olfactory receptor (OR) genes [12-16]. However, with thousands of aromas and few deorphaned ORs [17, 18], there has been little progress toward linking variation at OR loci to...
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