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Article

Mutations in eIF4ENIF1 are associated with primary ovarian insufficiency.

The Journal of clinical endocrinology and metabolism - 1 Sept 2013

Kasippillai Thushiga, MacArthur Daniel G, Kirby Andrew, Thomas Brett, Lambalk Cornelius B, Daly Mark J, Welt Corrine K

Abstract excerpt

CONTEXT: Primary ovarian insufficiency (POI), or premature ovarian failure, results from ovarian follicle depletion with a consequent elevation of FSH levels before age 40 years. We identified a family in which 9 women in 3 consecutive generations developed menopause at approximately age 30 years. We hypothesized a genetic cause with a dominant mode of inheritance. DESIGN: This was a family-based genetic study...

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Share to Genetic Predisposition to Disease
Share to Menopause, Premature

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Nucleocytoplasmic Transport Proteins

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Source

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Identifiers

PMID: 23902945
DOI: 10.1210/jc.2013-1102
PMCID: PMC5393467

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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