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Article

Mannan core branching of lipo(arabino)mannan is required for mycobacterial virulence in the context of innate immunity

31 Jul 2013

Abstract excerpt

The causative agent of tuberculosis (TB), Mycobacterium tuberculosis, remains an important worldwide health threat. Although TB is one of the oldest infectious diseases of man, a detailed understanding of the mycobacterial mechanisms underlying pathogenesis remains elusive. Here, we studied the role of the α(1→2) mannosyltransferase MptC in mycobacterial virulence, using the Mycobacterium marinum zebrafish...

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PMID: 23902464
DOI: 10.1111/cmi.12175

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