Article
A deletion within glycoprotein L of Marek's disease virus (MDV) field isolates correlates with a decrease in bivalent MDV vaccine efficacy in contact-exposed chickens.
Avian diseases - 1 Jun 2009
Tavlarides-Hontz Phaedra, Kumar Pankaj M, Amortegui Juliana Rojas, Osterrieder Nikolaus, Parcells Mark S
Abstract excerpt
We examined the functional role of a naturally occurring deletion within the glycoprotein L (gL) gene of Marek's disease virus (MDV) field isolates. We previously showed that this mutation incrementally increased the virulence of an MDV in contact-exposed SPF leghorn chickens, when chickens shedding this virus were co-infected with herpesvirus of turkeys (HVT). In our present study, we examined this mutation...
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