Article
Characterization of assembly intermediates containing subunit 1 of yeast cytochrome oxidase.
The Journal of biological chemistry - 13 Sept 2013
McStay Gavin P, Su Chen-Hsien, Thomas Susan M, Xu Jonathan Tong, Tzagoloff Alexander
Abstract excerpt
Mitochondrial-encoded Cox1p, one of the three core subunits of yeast cytochrome oxidase (COX), was previously shown to associate with regulatory proteins and nuclear-encoded subunits into five high molecular weight complexes that were proposed to constitute the pathway for biogenesis of the Cox1p assembly module. One of the intermediates (D5) was inferred, but not directly shown to exist. In the present study...
Topics
- Alleles
- Cell Nucleus
- Electron Transport Complex IV
- Gene Expression Regulation, Enzymologic
- Gene Expression Regulation, Fungal
- Holoenzymes
- Mitochondria
- Mutation
- Protein Structure, Tertiary
- Saccharomyces cerevisiae