Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LncRNA SOX2‐OT is a novel prognostic biomarker for osteosarcoma patients and regulates osteosarcoma cells proliferation and motility through modulating SOX2

29 Sept 2017

Abstract excerpt

Long noncoding RNA (LncRNA) SOX2 overlapping transcript (SOX2-OT) has been shown to serve an oncogenic role in human lung cancer, hepatocellular carcinoma, and gastric cancer. However, the clinical significance and biological function of lncRNA SOX2-OT in osteosarcoma are still unclear. LncRNA SOX2-OT expression was measured in osteosarcoma tissues and cell lines. Loss-of-function and gain-of-function studies...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Mycobacterium research and diagnosis
Share to Sarcoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28960757
DOI: 10.1002/iub.1681

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LncRNA SOX2‐OT is a novel prognostic biomarker for osteosarcoma patients and regulates osteosarcoma cells proliferation and motility through modulating SOX2PMID 28960757Read ↗

Sox2 is required for tumor development and cancer cell proliferation in osteosarcomaSemantic proximity Read ↗

Overexpression of the non-coding SOX2OT variants 4 and 7 in lung tumors suggests an oncogenic role in lung cancer.Semantic proximity Read ↗

Clinical Correlation of Transcription Factor SOX3 in Cancer: Unveiling Its Role in TumorigenesisSemantic proximity Read ↗

SOX12 Promotes Thyroid Cancer Cell Proliferation and Invasion by Regulating the Expression of POU2F1 and POU3F1Semantic proximity Read ↗

SOX2 Targets Fibronectin 1 to Promote Cell Migration and Invasion in Ovarian Cancer: New Molecular Leads for Therapeutic InterventionSemantic proximity Read ↗

Long non-coding RNA SOX2OT promotes the stemness phenotype of bladder cancer cells by modulating SOX2Semantic proximity Read ↗

LncRNA CCAT2 promoted osteosarcoma cell proliferation and invasionSemantic proximity Read ↗

MicroRNA-532-5p is a prognostic marker and inhibits the aggressive phenotypes of osteosarcoma through targeting CXCL2.Semantic proximity Read ↗

KLF8 promotes cancer stem cell-like phenotypes in osteosarcoma through miR-429-SOX2 signaling.Semantic proximity Read ↗

LINC00266-1/miR-548c-3p/SMAD2 feedback loop stimulates the development of osteosarcoma.Semantic proximity Read ↗

Sox2 nuclear expression is closely associated with poor prognosis in patients with histologically node-negative oral tongue squamous cell carcinomaSemantic proximity Read ↗

Silencing SOX2 Induced Mesenchymal-Epithelial Transition and Its Expression Predicts Liver and Lymph Node Metastasis of CRC PatientsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.