Article
Limustin®, a non-innovator tacrolimus formulation, yields reduced drug exposure in pediatric renal transplant recipients.
Pediatric transplantation - 1 Nov 2014
Jacobo-Cabral Carlos O, García-Roca Pilar, Reyes Herlinda, Lozada-Rojas Lucero, Cruz-Antonio Leticia, Medeiros Mara, Castañeda-Hernandez Gilberto
Abstract excerpt
The aim of this study was to evaluate the bioavailability of two oral tacrolimus formulations, the innovator Prograf(®) and a formulation commercialized in Mexico with the brand name Limustin(®), in children. Stable Mexican pediatric renal transplant recipients received the product authorized by their social security provider, being either Prograf(®) or Limustin(®). At steady state, blood samples were drawn and...
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