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Mutagenicity and recombinagenicity of Ocotea acutifolia (Lauraceae) aporphinoid alkaloids.

Mutation research - 18 Sept 2013

Guterres Zaira da Rosa, da Silva Ana Francisca Gomes, Garcez Walmir Silva, Garcez Felipe Rodrigues, Fernandes Carlos Alexandre, Garcez Fernanda Rodrigues

Abstract excerpt

The somatic mutation and recombination test (SMART) in wing cells of Drosophila melanogaster was used to test the mutagenic and recombinogenic activities of five aporphinoid alkaloids isolated from Ocotea acutifolia: thalicminine (1), (+)-dicentrine (2), (+)-ocoteine (3), (+)-6S-ocoteine N-oxide (4), and (+)-leucoxine (5). Third-stage larvae derived from the standard cross with wing cell markers mwh and/or flr(3)...

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PMID: 23892138
DOI: 10.1016/j.mrgentox.2013.07.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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