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Article

Cross-species sensitivity to a novel androgen receptor agonist of potential environmental concern, spironolactone

23 Jul 2013

Abstract excerpt

Spironolactone is a pharmaceutical that in humans is used to treat conditions like hirsutism, various dermatologic afflictions, and female-pattern hair loss through antagonism of the androgen receptor. Although not routinely monitored in the environment, spironolactone has been detected downstream of a pharmaceutical manufacturer, indicating a potential for exposure of aquatic species. Furthermore, spironolactone...

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PMID: 23881739
DOI: 10.1002/etc.2330

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