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Detection of anti-androgenic activity of chemicals in fish studies: a data review

28 May 2023

Abstract excerpt

A systematic review was conducted on the sensitivity of fish testing guidelines to detect the anti-androgenic activity of substances. Sequence Alignment to Predict Across Species Susceptibility (SeqAPASS) was used to investigate the conservation of the androgen receptor (AR) between humans and fish, and among fish species recommended in test guidelines. The AR is conserved between fish species and humans (i.e....

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PMID: 37526219
DOI: 10.1080/10408444.2023.2232398

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