Article
Polymorphisms in the genes related to angiogenesis are associated with uterine cervical cancer.
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society - 1 Sept 2013
Ramos-Flores Christian, Romero-Gutiérrez Teresa, Delgado-Enciso Iván, Maldonado Gabriela Enríquez, Plascencia Víctor Montaño, Vazquez-Vuelvas Oscar F, Quintero-Ramos Antonio, Mejía Roberto Chaparro, Espinoza-Gomez Francisco, Baltazar-Rodriguez Luz M, Valdez-Velazquez Laura L
Abstract excerpt
INTRODUCTION: The expression of plasminogen activator inhibitor type 1 (PAI-1), vascular endothelial growth factor (VEGF), and transforming growth factor β1 (TGF-β1) participates in the angiogenesis of several cancer types. The goal of this study was to investigate polymorphisms in genes related to angiogenesis (PAI-1-675 4G/5G, VEGF C936T, and TGF-β1 G-800A) to evaluate the risk for developing uterine cervical...
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