Article
Color-changing mutation in the E-F loop of proteorhodopsin.
Biochemistry - 26 May 2009
Yoshitsugu Maiko, Yamada Junya, Kandori Hideki
Abstract excerpt
It is usually assumed that only amino acids located near the retinal chromophore are responsible for color tuning of rhodopsins. However, we recently found that replacement of Ala178 with Arg in the E-F loop of proteorhodopsin (PR), an archaeal-type rhodopsin in marine bacteria, shifts the lambda(max) from 525 to 545 nm at neutral pH [Yoshitsugu, M., Shibata, M., Ikeda, D., Furutani, Y., and Kandori, H. (2008)...
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