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Article

MiR-19b/20a/92a regulates the self-renewal and proliferation of gastric cancer stem cells

1 Jan 2013

Abstract excerpt

Human gastric cancers contain a population of gastric cancer stem cells (GCSCs) that can undergo self-renewal and multipotent differentiation. GCSCs can be enriched with EpCAM+/CD44+ gastric cancer cells. However, the underlying mechanisms controlling the balance of GCSC self-renewal and differentiation remain to be explored. Because miRNAs can regulate cancer cell fates, we compared miRNA expression in...

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PMID: 23868977
DOI: 10.1242/jcs.127944

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