Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MiR-19a promotes epithelial-mesenchymal transition through PI3K/AKT pathway in gastric cancer.

International journal of clinical and experimental pathology - 1 Jan 2014

Lu Weidong, Xu Zhen, Zhang Min, Zuo Yun

Abstract excerpt

It has been reported that miR-19a was up-regulated in gastric cancer (GC), playing an oncogenic role. However, the underlying mechanism is still unknown. Therefore, in our present study, we investigated the role of miR-19a in gastric tissues as well as 2 GC cell lines. In vivo in clinical tissue level, we have detected basal expression level of miR-19a using real-time reversal transcriptional PCR (RT-PCR); in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Enzyme Activation
Share to Epithelial-Mesenchymal Transition

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplasm Invasiveness

Share to Phosphatidylinositol 3-Kinase

Share to Phosphoinositide-3 Kinase Inhibitors

Share to Proto-Oncogene Proteins c-akt

Share to RNA Interference

Share to Stomach Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 25400827
PMCID: PMC4230128

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MiR-19a promotes epithelial-mesenchymal transition through PI3K/AKT pathway in gastric cancer.PMID 25400827Read ↗

Sp1-driven up-regulation of miR-19a decreases RHOB and promotes pancreatic cancerSemantic proximity Read ↗

MiR-19a/b modulate the metastasis of gastric cancer cells by targeting the tumour suppressor MXD1.Semantic proximity Read ↗

The PLGF /c‐ MYC /miR‐19a axis promotes metastasis and stemness in gallbladder cancerSemantic proximity Read ↗

MiR-19b/20a/92a regulates the self-renewal and proliferation of gastric cancer stem cellsSemantic proximity Read ↗

miR-19a Promotes Cell Growth and Tumorigenesis through Targeting SOCS1 in Gastric CancerSemantic proximity Read ↗

MicroRNA-19b-3p suppresses gastric cancer development by negatively regulating Neuropilin-1Semantic proximity Read ↗

MicroRNA-200b reduced ZEB1 to inhibit cell proliferation and migration in human gastric cancerSemantic proximity Read ↗

Upregulation of the GRIM-19 gene suppresses invasion and metastasis of human gastric cancer SGC-7901 cell lineSemantic proximity Read ↗

MicroRNA-19a functions as an oncogene by regulating PTEN/AKT/pAKT pathway in myelomaSemantic proximity Read ↗

miR-19a correlates with poor prognosis of clear cell renal cell carcinoma patients via promoting cell proliferation and suppressing PTEN/SMAD4 expressionSemantic proximity Read ↗

MicroRNA-339, an epigenetic modulating target is involved in human gastric carcinogenesis through targeting NOVA1.Semantic proximity Read ↗

miR‑29a‑3p represses proliferation and metastasis of gastric cancer cells via attenuating HAS3 levels.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.