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Article

Bmi-1 regulates stem cell-like properties of gastric cancer cells via modulating miRNAs

20 Sept 2016

Abstract excerpt

BACKGROUND: B cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) plays an important role in regulating stemness in some kinds of cancer. However, the mechanisms remain unclear. This study was to investigate whether and how Bmi-1 regulates stemness of gastric cancer. METHODS: We firstly explored the role of Bmi-1 in regulating stem cell-like features in gastric cancer. Secondly, we screened out...

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PMID: 27644439
DOI: 10.1186/s13045-016-0323-9

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