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Article

Toll-like receptor genetic variants are associated with Gram-negative infections in VLBW infants.

Journal of perinatology : official journal of the California Perinatal Association - 1 Oct 2013

Sampath V, Mulrooney N P, Garland J S, He J, Patel A L, Cohen J D, Simpson P M, Hines R N

Abstract excerpt

OBJECTIVE: To test the hypothesis that single-nucleotide polymorphisms (SNPs) in Toll-like receptor (TLR) genes alter susceptibility to bacterial infections and modulate white blood cell (WBC) counts during infections in very low birth weight (VLBW) infants (birth weight <1500 g). STUDY DESIGN: VLBW infants recruited in a multicenter study were genotyped for nine functional TLR SNPs and associations between SNPs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23867959
DOI: 10.1038/jp.2013.80
PMCID: PMC4465440

Genes

TLR4
IRAK1
TLR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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