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Article

Role of polymorphic variants as genetic modulators of infection in neonatal sepsis.

Pediatric research - 1 Oct 2010

Abu-Maziad Asmaa, Schaa Kendra, Bell Edward F, Dagle John M, Cooper Margaret, Marazita Mary L, Murray Jeffrey C

Abstract excerpt

This study is a retrospective, case control study involving 535 preterm infants examining the roles of sequence polymorphisms in genes that mediate host immune responses to bacterial infection in newborn infants. A total of 49 single nucleotide polymorphisms (SNPs) in 19 candidate genes including inflammatory cytokines (IL6, IL10, IL1B, and TNF), cytokine receptors (IL1RN), toll-like receptors (TLR2, TLR4, and...

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Source

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Identifiers

PMID: 20463618
DOI: 10.1203/PDR.0b013e3181e6a068
PMCID: PMC2940937

Genes

TLR2
TLR5
TLR4
TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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