IEF-microheterogeneity of human PK-R: applicability for prenatal diagnosis.

Abstract excerpt

Microheterogeneity of human erythrocyte pyruvate kinase (PK-R) can be obtained by isoelectric focusing (IEF) in ultrathin polyacrylamide gels followed by immunological visualization methods. Using this method to study whether a polymorphismus of PK-R occurs, we could not find any deviations from the normal PK pattern in the case of samples from 100 German donors as well as at a lower number of PK samples from...

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