Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Functional ERAP1 Variants Distinctively Associate with Ankylosing Spondylitis Susceptibility under the Influence of HLA-B27 in Taiwanese.

Cells - 5 Aug 2022

Wang Chin-Man, Liu Ming-Kun, Jan Wu Yeong-Jian, Lin Jing-Chi, Zheng Jian-Wen, Wu Jianming, Chen Ji-Yih

Abstract excerpt

Epistasis of ERAP1 single nucleotide variations (SNVs) and HLA-B27 has been linked to ankylosing spondylitis susceptibility (AS). The current study examined how prevalent ERAP1 allelic variants (SNV haplotypes) in Taiwan affect ERAP1 functions and AS susceptibility in the presence or absence of HLA-B27. Sanger sequencing was used to discover all ERAP1 coding SNVs and common allelic variants in Taiwanese...

Topics

Join the communities discussing this publication.

Aminopeptidases
Genetic Predisposition to Disease
HLA-B27 Antigen
Leukocytes, Mononuclear
Minor Histocompatibility Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Spondylitis, Ankylosing

Source

Open in PubMed Open full text

Identifiers

PMID: 35954271
DOI: 10.3390/cells11152427
PMCID: PMC9368314

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Functional ERAP1 Variants Distinctively Associate with Ankylosing Spondylitis Susceptibility under the Influence of HLA-B27 in Taiwanese.PMID 35954271Read ↗

Association study of ankylosing spondylitis and polymorphisms in ERAP1 gene in Zhejiang Han Chinese population.Semantic proximity Read ↗

ERAP1 genetic variations associated with HLA-B27 interaction and disease severity of syndesmophytes formation in Taiwanese ankylosing spondylitis.Semantic proximity Read ↗

A polymorphism in ERAP1 is associated with susceptibility to ankylosing spondylitis in a Turkish population.Semantic proximity Read ↗

The association between seven ERAP1 polymorphisms and ankylosing spondylitis susceptibility: a meta-analysis involving 8,530 cases and 12,449 controls.Semantic proximity Read ↗

Association of HLA-B27 and ERAP1 with ankylosing spondylitis susceptibility in Beijing Han Chinese.Semantic proximity Read ↗

Associations between ERAP1 polymorphisms and ankylosing spondylitis susceptibility in HLA-B27 positive population: a Meta-analysis and bioinformatics analysis.Semantic proximity Read ↗

Association of polymorphisms in ERAP1 and risk of ankylosing spondylitis in a Chinese population.Semantic proximity Read ↗

ERAP1 variants are associated with ankylosing spondylitis in East Asian population: a new Chinese case-control study and meta-analysis of published series.Semantic proximity Read ↗

Functional variants of ERAP1 gene are associated with HLA-B27 positive spondyloarthritis.Semantic proximity Read ↗

Association between ERAP1 gene polymorphisms and ankylosing spondylitis susceptibility in Han population.Semantic proximity Read ↗

Association analysis of ERAP1 gene single nucleotide polymorphism in susceptibility to ankylosing spondylitis in Iranian populationSemantic proximity Read ↗

HLA-B*27 subtypes and their implications in the pathogenesis of ankylosing spondylitis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.