Article
Influence of nitrous oxide anesthesia, B-vitamins, and MTHFR gene polymorphisms on perioperative cardiac events: the vitamins in nitrous oxide (VINO) randomized trial.
Anesthesiology - 1 Jul 2013
Nagele Peter, Brown Frank, Francis Amber, Scott Mitchell G, Gage Brian F, Miller J Philip
Abstract excerpt
BACKGROUND: Nitrous oxide causes an acute increase in plasma homocysteine that is more pronounced in patients with the methylenetetrahydrofolate reductase (MTHFR) C677T or A1298C gene variant. In this randomized controlled trial, the authors sought to determine whether patients carrying the MTHFR C677T or A1298C variant had a higher risk for perioperative cardiac events after nitrous oxide anesthesia and whether...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.