Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Leukocyte DNA Damage and Wound Infection after Nitrous Oxide Administration

2 Apr 2013

Abstract excerpt

BACKGROUND: Nitrous oxide inactivates methionine synthase and may lead to DNA damage and wound infection. By using single-cell gel electrophoresis (comet assay), the authors determined the effect of nitrous oxide on DNA damage in circulating leukocytes. METHODS: In this double-blind, randomized controlled trial, 91 patients undergoing major colorectal surgery were randomized to receive 70% nitrous oxide (n = 31)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anesthesia and Neurotoxicity Research
Share to Folate and B Vitamins Research
Share to Nitric Oxide and Endothelin Effects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23549382
DOI: 10.1097/aln.0b013e31829107b8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Leukocyte DNA Damage and Wound Infection after Nitrous Oxide AdministrationPMID 23549382Read ↗

Influence of nitrous oxide anesthesia, B-vitamins, and MTHFR gene polymorphisms on perioperative cardiac events: the vitamins in nitrous oxide (VINO) randomized trial.Semantic proximity Read ↗

Oxidative DNA damage and oxidative stress in subjects occupationally exposed to nitrous oxide (N(2)O).Semantic proximity Read ↗

Nitric oxide-induced genotoxicity, mitochondrial damage, and apoptosis in human lymphoblastoid cells expressing wild-type and mutant p53Semantic proximity Read ↗

Modulation of gene expression and influence of gene polymorphisms related to genotoxicity and redox status on occupational exposure to inhaled anesthetics.Semantic proximity Read ↗

Influence of methylenetetrahydrofolate reductase gene polymorphisms on homocysteine concentrations after nitrous oxide anesthesia.Semantic proximity Read ↗

DNA Deaminating Ability and Genotoxicity of Nitric Oxide and its ProgenitorsSemantic proximity Read ↗

The effects of nitrous oxide on vitamin B12 and homocysteine levels in methyltetrahydrofolate reductase gene mutation.Semantic proximity Read ↗

Threshold Effects of Nitric Oxide-Induced Toxicity and Cellular Responses in Wild-Type and p53-Null Human Lymphoblastoid CellsSemantic proximity Read ↗

DNA damage after long-term repetitive hyperbaric oxygen exposureSemantic proximity Read ↗

Relatively Small Increases in the Steady-State Levels of Nucleobase Deamination Products in DNA from Human TK6 Cells Exposed to Toxic Levels of Nitric OxideSemantic proximity Read ↗

Nitrous oxide in pediatric anesthesia: friend or foe?Semantic proximity Read ↗

DNA Cross-linking, Double-Strand Breaks, and Apoptosis in Corneal Endothelial Cells after a Single Exposure to Mitomycin CSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.