Article
Retroviral nucleocapsid protein-metal ion interactions: folding and sequence variants.
Proceedings of the National Academy of Sciences of the United States of America - 1 Aug 1990
Green L M, Berg J M
Abstract excerpt
Retroviral nucleocapsid proteins contain one or two proposed metal-binding sequences of the form Cys-Xaa2-Cys-Xaa4-His-Xaa4-Cys. Previously, we reported that an 18-amino acid peptide derived from the nucleocapsid protein of Rauscher murine leukemia virus (RMLV) binds metals such as Co2+ and Zn2+. We have now synthesized the entire nucleocapsid protein from RMLV. We report here that the protein also binds Co2+ and...
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