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Article

Variable promoter methylation contributes to differential expression of key genes in human placenta-derived venous and arterial endothelial cells

15 Jul 2013

Abstract excerpt

BACKGROUND: The endothelial compartment, comprising arterial, venous and lymphatic cell types, is established prenatally in association with rapid phenotypic and functional changes. The molecular mechanisms underpinning this process in utero have yet to be fully elucidated. The aim of this study was to investigate the potential for DNA methylation to act as a driver of the specific gene expression profiles of...

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PMID: 23855827
DOI: 10.1186/1471-2164-14-475

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