Article
[Analysis of genetic diversity of HIV-1 nef genes from a patient with AIDS dementia complex].
Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology - 1 Feb 2013
He Shu-ting, Chi Yuan-yuan, Pu Shaung-shuang, Liu Jian-wei, Wen Hong-ling, Wang Zhi-yu, Song Yan-yan, Xu Hong-zhi, Zhao Li
Abstract excerpt
OBJECTIVE: To study the genetic diversity of HIV-1 nef genes from a patient with AIDS dementia complex(ADC) , so as to research the amino acid variability and the pathogenesis of ADC. METHODS: The nef gene was amplified with PCR from genomic DNA which was extracted from spleen and different brain tissues(basal ganglia, frontal gray matter, meninges, temporal lobe)of a patient who died of ADC. PCR products were...
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