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Article

Notch signal regulates corneal endothelial-to-mesenchymal transition.

The American journal of pathology - 1 Sept 2013

Li Cheng, Dong Fei, Jia Yanni, Du Huiyi, Dong Nuo, Xu Yajie, Wang Shen, Wu Huping, Liu Zuguo, Li Wei

Abstract excerpt

Endothelial-to-mesenchymal transition (EnMT) is a cell transformation process involved in both morphogenesis and pathogenesis. EnMT of corneal endothelial cells happens after endothelial injury and during ex vivo culture. Previous studies have shown that the transforming growth factor-β signaling pathway is involved in this transition. In this study, we found that rat corneal endothelial cells could spontaneously...

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Identifiers

PMID: 23850080
DOI: 10.1016/j.ajpath.2013.05.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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