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Article

Second-order approximations for selection coefficients at polygenic loci.

Journal of mathematical biology - 1 Jan 1990

Hastings A

Abstract excerpt

I determine the second-order approximation for the phenotypic distribution of a quantitative trait, ignoring the effects of epistasis and linkage disequilibrium, conditioned on the presence of a specified genotype at one underlying locus of small effect. I demonstrate that this approximation has an error that is third order in the allelic or genotypic effects, independent of the form of the phenotypic...

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Identifiers

PMID: 2384723
DOI: 10.1007/BF00178330

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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