Article
Detection of single-nucleotide variations by monitoring the blinking of fluorescence induced by charge transfer in DNA.
Chembiochem : a European journal of chemical biology - 19 Aug 2013
Kawai Kiyohiko, Majima Tetsuro, Maruyama Atsushi
Abstract excerpt
Charge transfer dynamics in DNA: Photo-induced charge separation and charge-recombination dynamics in DNA was assessed by monitoring the blinking of fluorescence. Single nucleotide variations, mismatch and one base deletion, were differentiated based on the length of the off-time of the blinking, which corresponds to the lifetime of the charge-separated state.
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