Article
Combination assays for evaluation of immune function and CYP3A5 genotype to identify the risk of infectious complications and mortality in living donor liver transplant patients.
Annals of transplantation - 11 Jul 2013
Mizuno Shugo, Nakatani Kaname, Muraki Yuichi, Tanemura Akihiro, Azumi Yoshinori, Kuriyama Naohisa, Ohsawa Ichiro, Kishiwada Masashi, Usui Masanobu, Sakurai Hiroyuki, Tabata Masami, Okuda Masahiro, Nobori Tsutomu, Isaji Shuji
Abstract excerpt
BACKGROUND: The aim of this study is to evaluate whether the combination of the ImmuKnow assay (IMK) and cytochrome P450 3A5 (CYP3A5) genotype assay is useful for identifying the risk of morbidity and mortality in living donor liver transplantation (LDLT) patients, and also to investigate the optimal cutoff value of IMK level of immune status. MATERIAL AND METHODS: Sixty six LDLT patients, who were randomly...
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