Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?

doi:10.1371/journal.pone.0067650

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?

PloS one - 1 Jan 2013

Dorajoo Rajkumar, Li Ruoying, Ikram Mohammad Kamran, Liu Jianjun, Froguel Philippe, Lee Jeannette, Sim Xueling, Ong Rick Twee-Hee, Tay Wan Ting, Peng Chen, Young Terri L, Blakemore Alexandra I F, Cheng Ching Yu, Aung Tin, Mitchell Paul, Wang Jie Jin, Klaver Caroline C, Boerwinkle Eric, Klein Ronald, Siscovick David S, Jensen Richard A, Gudnason Vilmundur, Smith Albert Vernon, Teo Yik Ying, Wong Tien Yin, Tai E-Shyong, Heng Chew-Kiat, Friedlander Yechiel

Abstract excerpt

INTRODUCTION: C-reactive protein (CRP) levels are associated with cardiovascular disease and systemic inflammation. We assessed whether CRP-associated loci were associated with serum CRP and retinal markers of microvascular disease, in Asian populations. METHODS: Genome-wide association analysis (GWAS) for serum CRP was performed in East-Asian Chinese (N = 2,434) and Malays (N = 2,542) and South-Asian Indians...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to C-Reactive Protein

Share to Cytokines

Share to Genetic Loci

Share to Hepatocyte Nuclear Factor 1-alpha

Share to Microvessels

Share to Receptors, Leptin

Share to Singapore

Source

Open in PubMed Open full text

Identifiers

PMID: 23844046
DOI: 10.1371/journal.pone.0067650
PMCID: PMC3699653

Genes

CRP
APOE
GCKR
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Are C-reactive protein associated genetic variants associated with serum levels and retinal markers of microvascular pathology in Asian populations from Singapore?PMID 23844046Read ↗

Association of C-Reactive Protein Genetic Polymorphisms With Late Age-Related Macular Degeneration.Semantic proximity Read ↗

C-reactive protein genetic variant is associated with diabetic retinopathy in Chinese patients with type 2 diabetes.Semantic proximity Read ↗

A genome-wide association study of high-sensitivity C-reactive protein in a large Korean population highlights its role in cholesterol metabolismSemantic proximity Read ↗

Genetic risk assessment for cardiovascular disease with seven genes associated with plasma C-reactive protein concentrations in Asian populations.Semantic proximity Read ↗

Genetic determinants of C-reactive protein.Semantic proximity Read ↗

Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study.Semantic proximity Read ↗

Association of common CRP gene variants with CRP levels and cardiovascular events.Semantic proximity Read ↗

C-reactive protein as a predictor of hypertension in the Hong Kong Cardiovascular Risk Factor Prevalence Study (CRISPS) cohort.Semantic proximity Read ↗

C-reactive protein (CRP) gene polymorphisms, CRP levels and risk of incident essential hypertension: findings from an observational cohort of Han Chinese.Semantic proximity Read ↗

Genetic variation in C-reactive protein (CRP) gene may be associated with risk of systemic lupus erythematosus and CRP concentrations.Semantic proximity Read ↗

Genetic Loci associated with C-reactive protein levels and risk of coronary heart disease.Semantic proximity Read ↗

Genome-wide association with C-reactive protein levels in CLHNS: evidence for the CRP and HNF1A loci and their interaction with exposure to a pathogenic environment.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.