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Infectious Bronchitis Virus as a Vector for the Expression of Heterologous Genes

26 Jun 2013

Abstract excerpt

The avian coronavirus infectious bronchitis virus (IBV) is the causative agent of the respiratory disease infectious bronchitis of domestic fowl, and is controlled by routine vaccination. To explore the potential use of IBV as a vaccine vector a reverse genetics system was utilised to generate infectious recombinant IBVs (rIBVs) expressing the reporter genes enhanced green fluorescent protein (eGFP) or humanised...

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PMID: 23840781
DOI: 10.1371/journal.pone.0067875

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