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Article

Altered Methylation of IGF2 Locus 20 Years after Preterm Birth at Very Low Birth Weight

19 Jun 2013

Abstract excerpt

INTRODUCTION: People born preterm at very low birth weight (VLBW, ≤1500g) have higher rates of risk factors for adult-onset diseases, including cardiovascular diseases and type 2 diabetes. These risks may be mediated through epigenetic modification of genes that are critical to normal growth and development. METHODS: We measured the methylation level of an imprinted insulin-like-growth-factor 2 (IGF2) locus...

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PMID: 23840686
DOI: 10.1371/journal.pone.0067379

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