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Article

Tacrolimus dose requirement in pediatric liver transplantation: influence of CYP3A5 gene polymorphism.

Pharmacogenomics - 1 Jul 2013

Durand Philippe, Debray Dominique, Kolaci Mikaela, Bouligand Jerome, Furlan Valérie, Fabre Monique, Letierce Alexia, Verstuyft Céline, Becquemont Laurent

Abstract excerpt

AIM: Little information is available regarding the influence of CYP3A5 genetic polymorphisms on tacrolimus dose requirement in pediatric liver transplantation. PATIENTS & METHODS: We performed a retrospective study among 179 pediatric liver recipients grafted between 2002 and 2009 in order to determine the influence of donor CYP3A5 genotype along with clinical variables on tacrolimus daily dose requirement during...

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Source

Identifiers

PMID: 23837476
DOI: 10.2217/pgs.13.87

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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