Article
Causal relationship between adiponectin and metabolic traits: a Mendelian randomization study in a multiethnic population.
PloS one - 1 Jan 2013
Mente Andrew, Meyre David, Lanktree Matthew B, Heydarpour Mahyar, Davis A Darlene, Miller Ruby, Gerstein Hertzel, Hegele Robert A, Yusuf Salim, Anand Sonia S
Abstract excerpt
BACKGROUND: Adiponectin, a secretagogue exclusively produced by adipocytes, has been associated with metabolic features, but its role in the development of the metabolic syndrome remains unclear. OBJECTIVES: We investigated the association between serum adiponectin level and metabolic traits, using both observational and genetic epidemiologic approaches in a multiethnic population assembled in Canada. METHODS:...
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