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Article

Mendelian randomization study reveals a causal relationship between adiponectin and LDL cholesterol in Africans.

Scientific reports - 8 Nov 2022

Meeks Karlijn A C, Bentley Amy R, Doumatey Ayo P, Adeyemo Adebowale A, Rotimi Charles N

Abstract excerpt

Adiponectin has been associated with cardiometabolic traits in observational studies across populations, yet it is unclear if these associations are causal. We performed Mendelian randomization (MR) analysis to assess the relationship between adiponectin and cardiometabolic traits in sub-Saharan Africans. We constructed a polygenic risk score (PRS) for adiponectin levels across 3354 unrelated sub-Saharan...

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Identifiers

PMID: 36347891
DOI: 10.1038/s41598-022-21922-w
PMCID: PMC9643497

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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