Article
Molecular fingerprint of high fat diet induced urinary bladder metabolic dysfunction in a rat model.
PloS one - 1 Jan 2013
Oberbach Andreas, Jehmlich Nico, Schlichting Nadine, Heinrich Marco, Lehmann Stefanie, Wirth Henry, Till Holger, Stolzenburg Jens-Uwe, Völker Uwe, Adams Volker, Neuhaus Jochen
Abstract excerpt
AIMS/HYPOTHESIS: Diabetic voiding dysfunction has been reported in epidemiological dimension of individuals with diabetes mellitus. Animal models might provide new insights into the molecular mechanisms of this dysfunction to facilitate early diagnosis and to identify new drug targets for therapeutic interventions. METHODS: Thirty male Sprague-Dawley rats received either chow or high-fat diet for eleven weeks....
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