Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Experimental long-term diabetes mellitus alters the transcriptome and biomechanical properties of the rat urinary bladder

30 Jul 2021

Abstract excerpt

Diabetes mellitus (DM) is the leading cause of chronic kidney disease and diabetic nephropathy is widely studied. In contrast, the pathobiology of diabetic urinary bladder disease is less understood despite dysfunctional voiding being common in DM. We hypothesised that diabetic cystopathy has a characteristic molecular signature. We therefore studied bladders of hyperglycaemic and polyuric rats with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Glycation End Products research
Share to Aldose Reductase and Taurine
Share to Urinary Bladder and Prostate Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34330963
DOI: 10.1038/s41598-021-94532-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Experimental long-term diabetes mellitus alters the transcriptome and biomechanical properties of the rat urinary bladderPMID 34330963Read ↗

Proteomic Insights into Diabetic Cystopathy: Identifying Key Protein Expression Changes in Bladder TissueSemantic proximity Read ↗

Mechanisms of Action for Diabetic Bladder Dysfunction — State of the ArtSemantic proximity Read ↗

Molecular fingerprint of high fat diet induced urinary bladder metabolic dysfunction in a rat model.Semantic proximity Read ↗

Circulating exosomal miR-16-5p and let-7e-5p are associated with bladder fibrosis of diabetic cystopathySemantic proximity Read ↗

Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathySemantic proximity Read ↗

Single-cell transcriptomics reveals a mechanosensitive injury signaling pathway in early diabetic nephropathySemantic proximity Read ↗

ANRIL regulates multiple molecules of pathogenetic significance in diabetic nephropathySemantic proximity Read ↗

Abnormal cytoskeletal protein expression in cultured skin fibroblasts from type 1 diabetes mellitus patients with nephropathy: A proteomic approach.Semantic proximity Read ↗

Diabetic bladder dysfunction progresses from an overactive to an underactive phenotype in a type-1 diabetic mouse model (Akita female mouse) and is dependent on NLRP3.Semantic proximity Read ↗

Insights into Diabetic Kidney Disease Using Urinary Proteomics and BioinformaticsSemantic proximity Read ↗

Urinary Collagen Fragments Are Significantly Altered in Diabetes: A Link to PathophysiologySemantic proximity Read ↗

Discovery of genes related to diabetic nephropathy in various animal models by current techniques.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.