Article
Horizontally acquired glycosyltransferase operons drive salmonellae lipopolysaccharide diversity.
PLoS genetics - 1 Jun 2013
Davies Mark R, Broadbent Sarah E, Harris Simon R, Thomson Nicholas R, van der Woude Marjan W
Abstract excerpt
The immunodominant lipopolysaccharide is a key antigenic factor for Gram-negative pathogens such as salmonellae where it plays key roles in host adaptation, virulence, immune evasion, and persistence. Variation in the lipopolysaccharide is also the major differentiating factor that is used to classify Salmonella into over 2600 serovars as part of the Kaufmann-White scheme. While lipopolysaccharide diversity is...
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