Article
SNP-based Bayesian networks can predict oral mucositis risk in autologous stem cell transplant recipients.
Oral diseases - 1 Oct 2013
Sonis St, Antin Jh, Tedaldi Mw, Alterovitz G
Abstract excerpt
OBJECTIVE: Approximately 40% of patients receiving conditioning chemotherapy prior to autologous hematopoietic stem cell transplants (aHSCT) develop severe oral mucositis (SOM). Aside from disabling pain, ulcerative lesions associated with SOM predispose to poor health and economic outcomes. Our objective was to develop a probabilistic graphical model in which a cluster of single-nucleotide polymorphisms (SNPs)...
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