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Haplotypes of the IL-1 gene cluster are associated with gastroesophageal reflux disease and Barrett's esophagus.

Human immunology - 1 Sept 2013

Izakovicova Holla Lydie, Borilova Linhartova Petra, Hrdlickova Barbara, Marek Filip, Dolina Jiri, Rihak Vladimir, Kala Zdenek

Abstract excerpt

OBJECTIVES: Gastroesophageal reflux (GERD) is a one of the major public health problem that can lead to reflux esophagitis (RE), Barrett's esophagus (BE), and esophageal adenocarcinoma (EAC). The aim of our study was to determine the impact of IL-1 gene polymorphisms on the development of GERD, RE and BE. METHODS: Three hundred and thirty-three Czech patients with gastroesophageal reflux and 165 healthy controls...

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PMID: 23806268
DOI: 10.1016/j.humimm.2013.06.026

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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