Article
Associations of CYP1A1, GSTM1 and GSTT1 polymorphisms with lung cancer susceptibility in a Northern Indian population.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013
Shukla R K, Tilak A R, Kumar C, Kant S, Kumar A, Mittal B, Bhattacharya S
Abstract excerpt
BACKGROUND: Susceptibility to lung cancer has been shown to be modulated by inheritance of polymorphic genes encoding cytochrome P450 1A1 (CYP1A1) and glutathione S transferases (GSTM1 and GSTT1), which are involved in the bioactivation and detoxification of environmental toxins. This might be a factor in the variation in lung cancer incidence with ethnicity. MATERIALS AND METHODS: We conducted a case-control...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
