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Article

Oncogenesis and the clinical significance of K-ras in pancreatic adenocarcinoma.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013

Huang Chun, Wang Wei-Min, Gong Jian-Ping, Yang Kang

Abstract excerpt

The RAS family genes encode small GTP-binding cytoplasmic proteins. Activated KRAS engages multiple effector pathways, notably the RAF-mitogen-activated protein kinase, phosphoinositide-3-kinase (PI3K) and RalGDS pathways. In the clinical field, K-ras oncogene activation is frequently found in human cancers and thus may serve as a potential diagnostic marker for cancer cells in circulation. This mini-review aims...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23803017
DOI: 10.7314/apjcp.2013.14.5.2699

Genes

KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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