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Article

Down-Regulated CK8 Expression in Human Intervertebral Disc Degeneration

1 Jan 2013

Abstract excerpt

As an intermediate filament protein, cytokeratin 8 (CK8) exerts multiple cellular functions. Moreover, it has been identified as a marker of notochord cells, which play essential roles in human nucleus pulposus (NP). However, the distribution of CK8 positive cells in human NP and their relationship with intervertebral disc degeneration (IDD) have not been clarified until now. Here, we found the percentage of CK8...

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PMID: 23801880
DOI: 10.7150/ijms.5642

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