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Article

In vitro integration of ribosomal RNA synthesis, ribosome assembly, and translation.

Molecular systems biology - 25 Jun 2013

Jewett Michael C, Fritz Brian R, Timmerman Laura E, Church George M

Abstract excerpt

Purely in vitro ribosome synthesis could provide a critical step towards unraveling the systems biology of ribosome biogenesis, constructing minimal cells from defined components, and engineering ribosomes with new functions. Here, as an initial step towards this goal, we report a method for constructing Escherichia coli ribosomes in crude S150 E. coli extracts. While conventional methods for E. coli ribosome...

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Identifiers

PMID: 23799452
DOI: 10.1038/msb.2013.31
PMCID: PMC3964315

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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